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A glycoconjugate vaccine against antimicrobial resistant Enterococci

Listing Description

Result description

Two enterococcal proteins SagA and PpiC were found to be promising immunogenic carrier proteins that can be used either conjugated to DHG or to other polysaccharides to develop multivalent vaccines formulations. We have developed a glycoconjugates composed of the proteins and the surface polysaccharide DHG which presents a broad coverage against infections caused by the Enterococcus faecalis and faecium.

Radical Innovation Breakthrough
Microbiome.

Addressing target audiences and expressing needs

Our needs are
  • Grants and Subsidies
We specifically need / are looking for

we are seeking for translating this vaccine candidate to proof of concept in humans, covering process optomization, scale up for production of GMP lot and first in human clinical trial

Target audiences
  • Public or private funding institutions
  • Research and Technology Organisations
  • Academia/ Universities

R&D, Technology and Innovation aspects

Current stage description

the preclinical proof of principle has been demonstrated

Result submitted to Horizon Results Platform by LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Offer Details

Specifications and Deliverables:

Value Proposition:

There is no vaccine available against Enterococci. one glycoconjugates would cover both E. faecalis and faecium. It could be first in the market.

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Adress:

GESCHWISTER SCHOLL PLATZ 1
MUNCHEN
Bavaria
80539
Germany

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