This topic seeks to enhance the maturity and scalability of biotech innovations in healthcare. Projects must:

• Focus on biological or bioengineered innovations with therapeutic potential (e.g., novel molecules, engineered proteins, gene editing tools, advanced drug delivery platforms, synthetic biology applications).

• Include a clear translational strategy with robust preclinical data and feasibility studies.

• Address manufacturing, safety, regulatory, and clinical aspects.

• Involve industry and end-user partners to validate the practical and commercial viability.

• Consider sex, gender, and population diversity in therapy design and validation.

Proposals should demonstrate a clear value chain from discovery to early clinical development, with potential to attract further investment or uptake by healthcare systems.